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With trichinosis, the same individual is sequentially first the definitive (final), and then the intermediate host, since at the stage of puberty Trichinella parasitizes in the mucous membrane of the small intestine, and at the stage of the larva - in the striated one.

Musculature. Infection with bionematoses occurs in different ways. So, dracunculiasis (rishta) is invaded by swallowing copepod crustaceans infected with rishta larvae with water; Trichinosis infection occurs when eating animal meat containing Trichinella larvae; filariasis are infected when bitten by intermediate hosts - mosquitoes, horseflies, midges. The distribution of nematodosis depends on the level of general and sanitary culture of people, their professions and working conditions, sanitary improvement of populated areas, the organization of medical prof.

Nematodes cause sensitization of the body with the development of allergic reactions, especially pronounced during the migration of larvae in the tissues, mechanically damage the tissues and organs of the host, and disrupt the functions of the body.

With a high intensity of invasion (see the complete body of knowledge) and intestinal localization, they reduce the absorption of nutrients and vitamins, which causes the development of anemia, aggravates the course of other diseases, suppresses immunity, slows down the development of children, reduces human capacity for work, and so on.

The changes observed in the body during Nematodosis depend on the localization of the pathological process; for example, with trichinosis, allergic myositis (see full body of knowledge), meningoencephalitis (see full body of knowledge), myocarditis (see full body of knowledge), systemic vasculitis (see full body of knowledge); with ascariasis, enterobiasis, trichocephalosis, ankylostomoses, signs of gastroduodenitis are found (see the complete body of knowledge Gastritis, Duodenitis), enterocolitis, less often inflammatory changes from other organs and systems. With all nematodes, changes of an allergic nature are observed: round-cell and eosinophilic infiltration in various organs and tissues, with the death of larvae in the tissues, the formation of granulomas.

Metformin picture of nematodosis is diverse. With the localization of pathogens in the intestine (for example, ascariasis, enterobiasis, and so on), abdominal pain, dyspeptic disorders are noted. When muscle pathogens are damaged (trichinosis), muscle pain occurs. Damage to the genitourinary and lymphatic systems, as well as the organ of vision, is observed with filariasis. With all nematoses, eosinophilia is noted. Sometimes nematodes proceed without symptoms. The diagnosis is based on clinical, epidemiological and laboratory data - the results of coprological, larvoscopic and immunological studies, blood tests (see the complete body of knowledge Helminthological research methods).

A person is susceptible to infection by pathogenic nematodes at any age. Children become infected more easily. After the disease, a temporary relative immunity develops, manifested by a decrease in the intensity of reinvasion, a slowdown in development and a reduction in the life span of nematodes, a decrease in the fertility of females, and the phenomenon of self-liberation of patients from parasites.

 

 

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Treatment of nematodosis is carried out with anti-nematodic drugs, which include piperazine, ditrazine, naphthamon (alcopar), difezil, levamizol (decaris), mebendazole (vermox) and others. The choice of the drug depends on the form of nematodose (see the complete body of knowledge in separate articles).